Surface-Bonded Antimicrobial Activity of an Organosilicon Quaternary Ammonium Chloride

  1. A. J. Isquith,                      
  2. E. A. Abbott           
  3. P. A. Walters

Author Affiliations - Biomedical Research and Development Laboratory, Dow Corning Corporation, Midland, Michigan 48640                     


The hydrolysis product of 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride exhibited antimicrobial activity against a broad range of microorganisms while chemically bonded to a variety of surfaces. The chemical was not removed from surfaces by repeated washing with water, and its antimicrobial activity could not be attributed to a slow release of the chemical, but rather to the surface-bonded chemical.